RemeGen grabs one of many world’s largest ever biotech IPOs

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RemeGen has raised $515 million on the Hong Kong alternate in one of many largest biotech IPOs ever produced.

The most important thus far in 2020, and one of many largest after Moderna’s $600 million-plus IPO a number of years again, the Yantai-based biotech in China will use its main money haul towards its wholesome pipeline of mid- to late-stage efforts.

This consists of telitacicept and disitamab vedotin, each slated for approval inside the subsequent three to eight months.

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An organization was dealing with main challenges in a worldwide scientific trial program with 30 research for an unusual indication. Not solely did they should transition all ongoing scientific trials to the Bioclinica Medical Adjudication platform for higher evaluation — however additionally they wanted to do it inside 60 days.

The previous remedy is geared toward B cell-mediated autoimmune illnesses, with an preliminary give attention to systemic lupus erythematosus, a situation that has seen its share of R&D setbacks, although a constant sequence of analysis lately has buoyed hopes of a renaissance within the space.

Disitamab vedotin, in the meantime, works as an in-demand antibody-drug conjugate concentrating on HER2 cancers, with a give attention to gastric, urothelial and HER2-low-expressing breast cancers.

Additional again within the pipeline, it additionally has a sequence of early-stage medicine engaged on fusion protein VEGFR/FGF in eye circumstances together with moist age-related macular degeneration and diabetic macular edema.

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